Comparison o f two agglutination tests (Toxolatex ® and Toxoscreen ®) for toxoplasmosis diagnosis: proposal of inclusion in a control program

Patrice Le Pape, Carlos A. Alvarez, Nidia Alvarez, .

Keywords: Screening tests, anti-toxoplasma antibodies, Serodiagnosis, latex agglutination test, direct agglutination test

Abstract

This study evaluated a latex agglutination test (Toxolatex ®, Fumouze) and a direct agglutination test using a whole antigen (Toxoscreen ®, Biomerieux) for the screening of toxoplasmosis antibodies, by means of comparison with the dye test (Sabin Feldman) (DT) and a fluorescent antibody test (IFAT). On 500 sera, a good correlation was obtained for these methods with DT (TI 96.8% and TS 98.6%) and IFAT (TL 95.4% and TS 97.2%). In addition to detecting antitoxoplasma immunoglobulin M antibodies. TL is a rauid, easy and inexpensive technique. Based these findings, we recommend the agglutination testior initial screening of specific antibodies against toxoplasmosis in seroepidemiological surveys and pregnancy control program.

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  • Patrice Le Pape Laboratoire de Parasitologie. Mycologie Médicale et lmmunologie Parasitaire, Inctitut de Biologie, CHU, Nantes. Service de Parasitologie et Biologie Animale, UFR de Pharmacie, Nantes
  • Carlos A. Alvarez Unidad de Infectología, Departamento de Medicina Interna. Facultad de Medicina, Universidad Nacional de Colombia, Santa Fe de Bogotá, D.C. Instituto de Salud en el Trópico, Facultad de Medicina. Universidad Nacional de Colombia, Santa Fe de Bogota, D.C.
  • Nidia Alvarez Laboratoire de Parasitologie. Mycologie Médicale et lmmunologie Parasitaire, Inctitut de Biologie, CHU, Nantes. Programa de Estudio y Control de Enfermedades Tropicales, PECET, Universidad de Antioquia, Medellín.
How to Cite
1.
Le Pape P, Alvarez CA, Alvarez N. Comparison o f two agglutination tests (Toxolatex ® and Toxoscreen ®) for toxoplasmosis diagnosis: proposal of inclusion in a control program. biomedica [Internet]. 2000 Jun. 1 [cited 2024 May 17];20(2):102-11. Available from: https://revistabiomedica.org/index.php/biomedica/article/view/1053
Published
2000-06-01
Section
Original articles

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