Calcium ATPase in the nervous system

Myriam L. Velandia, Zayra V. Garavito, María L. Caldas, Hernán Hurtado, .

Keywords: calcium, calcium ATPase, enzymatic cytochemistry, nervous system

Abstract

The calcium pump is an integral membrane protein, which regulates free citoplasmatic calcium using ATP energy. It controls citoplasmatic calcium concentrations below 0.1mM. It is located in all eucariotic cells in plasmalemma, sarcoendoplasmic reticulum and calciosomes. Its activity depends on ionic concentration, ATP hydrolysis and other regulators such as calmodulin, phospholipid and protein-kinases. This enzyme and its activity has been detected through several methods in the central nervous system as well as in other tissues.

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  • Myriam L. Velandia Laboratorio de Neurociencias, Instituto Nacional de Salud. Bogotá. D.C.
  • Zayra V. Garavito Laboratorio de Neurociencias, Instituto Nacional de Salud. Bogotá. D.C.
  • María L. Caldas Unidad de Microscopía y Análisis de Imagen. Instituto Nacional de Salud, Bogotá, D.C.
  • Hernán Hurtado Laboratorio de Neurociencias, Instituto Nacional de Salud. Bogotá. D.C.
How to Cite
1.
Velandia ML, Garavito ZV, Caldas ML, Hurtado H. Calcium ATPase in the nervous system. biomedica [Internet]. 2001 Mar. 1 [cited 2024 May 18];21(1):62-9. Available from: https://revistabiomedica.org/index.php/biomedica/article/view/1088
Published
2001-03-01
Section
Topic review

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