Image analysis to quantify S100-positive dendritic cells in leprosy-affected skin.

Luz H. Camargo, María Leonor Caldas, Marcela Neira, Ladys Sarmiento, .

DOI: https://doi.org/10.7705/biomedica.v23i2.1204
Keywords: image analysis, image processing, morphometry, langerhans cells
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Abstract

A morphometric analysis of skin dendritic cells was done on biopsies of patients with different forms of leprosy. An anti S100 antibody was used to determine dendritic cell quantity and extension. Patients with a better immune response to the bacillus showed a greater number of dendritic cells in the cases of dimorphic tuberculoid leprosy and tuberculoid leprosy. This result contrasted with that from patients with dimorphic lepromatous leprosy and lepromatous leprosy.

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  • Luz H. Camargo Unidad de Microscopía y Análisis de Imágenes, Instituto Nacional de Salud, Bogotá, D.C.
  • María Leonor Caldas Unidad de Microscopía y Análisis de Imágenes, Instituto Nacional de Salud, Bogotá, D.C.
  • Marcela Neira Laboratorio de Patología, Instituto Nacional de Salud, Bogotá, D.C.
  • Ladys Sarmiento Unidad de Microscopía y Análisis de Imágenes, Instituto Nacional de Salud, Bogotá, D.C.
How to Cite
1.
Camargo LH, Caldas ML, Neira M, Sarmiento L. Image analysis to quantify S100-positive dendritic cells in leprosy-affected skin. biomedica [Internet]. 2003 Jun. 1 [cited 2024 May 16];23(2):131-3. Available from: https://revistabiomedica.org/index.php/biomedica/article/view/1204
Published
2003-06-01
Issue
Vol. 23 No. 2 (2003)
Section
Imágenes en biomedicina

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