Chromosomal localization of the KMP-11 genes in the KP1(+) and KP1(-) strains of Trypanosoma rangeli.

Claudia Urueña, Paola Santander, Hugo Díez, Marleny Montilla, Ignacio Zarante, María del Carmen Thomas, Manuel Carlos López, Concepción Puerta, .

Keywords: Trypanosoma, Trypanosoma cruzi, cariotificación

Abstract

Genes encoding for the KMP-11 protein were localized on the chromosomes of Trypanosoma rangeli. These genes were located in two chromosomes of 3,100 and 3,400 kb in the KP1(-) strain whereas in the KP1(+) H14 and Choachí strains, the genes are located in a chromosome of 1,600 kb. The Choachí strain presents an additional band of 1,400 kb. In the Shubacbarina and Munanta strains of Trypanosoma cruzi, the KMP-11 genes are located on a chromosomal band of 1,490 kb. Therefore, the chromosomal localization of the KMP-11 genes presents a potential tool to differentiate among these parasites.

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  • Claudia Urueña Laboratorio de Parasitología Molecular, Departamento de Microbiología, Facultad de Ciencias, Pontifica Universidad Javeriana, Bogotá, DC, Colombia.
  • Paola Santander Laboratorio de Parasitología Molecular, Departamento de Microbiología, Facultad de Ciencias, Pontifica Universidad Javeriana, Bogotá, DC, Colombia.
  • Hugo Díez Laboratorio de Parasitología Molecular, Departamento de Microbiología, Facultad de Ciencias, Pontifica Universidad Javeriana, Bogotá, DC, Colombia.
  • Marleny Montilla Laboratorio de Parasitología, Instituto Nacional de Salud, Bogotá, D.C.
  • Ignacio Zarante Instituto de Genética, Facultad de Medicina, Pontificia Universidad Javeriana, Bogotá, D.C.
  • María del Carmen Thomas Laboratorio de Parasitología Molecular, Instituto de Parasitología y Biomedicina López-Neyra, CSIC, Granada
  • Manuel Carlos López Laboratorio de Parasitología Molecular, Instituto de Parasitología y Biomedicina López-Neyra, CSIC, Granada
  • Concepción Puerta Laboratorio de Parasitología Molecular, Departamento de Microbiología, Facultad de Ciencias, Pontifica Universidad Javeriana, Bogotá, D.C.
How to Cite
1.
Urueña C, Santander P, Díez H, Montilla M, Zarante I, Thomas M del C, et al. Chromosomal localization of the KMP-11 genes in the KP1(+) and KP1(-) strains of Trypanosoma rangeli. biomedica [Internet]. 2004 Jun. 1 [cited 2024 May 19];24(2):200-3. Available from: https://revistabiomedica.org/index.php/biomedica/article/view/1266

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Published
2004-06-01
Section
Short communication

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