Hiperplasia epitelial focal de la boca en Colombia (Enfermedad de Heck)

Abstract

The widespread distribution of focal epithelial hyperplasia (FEH) in Colombia, specially among indian is described. Our observation has been supported by the study of clinical data and biopsy specimens sent to us by physicians and dentists during their compulsory rural year. Lesions consist of numerous papules and nodules on the mucous surface of the lower lip, cheeks and tongue borders, affecting mainly children under 16 years of age and some adults. They present a chronic evolution lasting several years and are, generally, asymptomatic. Histopathology shows global epithelial hyperplasia with anastomoses of the rate pegs, "mitosis" cells, vacuolization and frequently, keratinocyte nucleation in the  upper external portion of the epithelium. Electron microscopy showed isolated visions and small intranuclear crystals of Papiloma virus in higher malpighian cells and in parakeratotic cells in the horny layer. Physicians and dentists should be well aware of the existence of FEH, specially those working with indian communities.