Hepatitis fulminante en la Sierra Nevada: Una forma de superinfección del virus delta con el virus de la hepatitis B.

Abstract

The paper presented hereby is an seroepidemiological study realized between September 1980 and October 1983; the study was carried out in a geographical region located in north Colombia South America. 258 persons were studied; Hepatitis A was found in 77 (93%). HBsAg or anti-HBs were detected in 30.5 to 55% among the inhabitants of two small towns (Santa Rosalia and Julio Sawady) in a third village (Aracataca) the frecuency was 2.5%, and 48.5% in the city of Santa Marta (population 250.000) evidence of exposure to Delta virus was confirmed in Julio Zawady and Santa Rosalia, 13.7% and 22% repectively, while in Aracataca Delta virus infection was negative. In 22 patientes fulminat Hepatitis was proved with serological evidence of hepatitis B infection, the mortabily was very high (65%) the results suggest that the fulminat Hepatitis in this regioncould be the result of coinfection of Delta and B virus.