Vasculitis granulomatosa centrofacial: estudio de seis casos y propuesta para su clasificación

Abstract

The number of cases, 2 of 6 localized and 4 generalized, which are presented, demonstrate that localized forms improve with medical treatment. Probably the problem is present due to a localised defect in a determined organ with antigenic presentation. This could improve since the defect is not a total change in the generalized form; the antigen could alter the macrophage source and could necessitate permanent treatment in a genetically susceptible person. The term lethal granuloma should not be used in those cases with a specifically defined diagnosis and the hypothesis is advanced that the term granulomatosis localised by Wegener should not be used, simply granulomatosis or localised vasculitis granuloma.