Collapsing glomerulonephritis with podocyte markers in hemophagocytic syndrome secondary to hepatosplenic T-cell lymphoma

María Adoración Martín-Gómez, Mercedes Caba-Molina, María José Viciana-Martínez-Lage, Rosa Ortega-Salas, Alicia Sánchez-Crespo, Manuel Jesús Soriano-Pérez, Mercedes Gómez-Morales, .

DOI: https://doi.org/10.7705/biomedica.v38i4.3893
Keywords: glomerulonefritis, linfohistiocitosis hemofagocítica, linfoma, insuficiencia renal, antígenos de diferenciación, trastornos linfoproliferativos
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Abstract

The hemophagocytic syndrome is a serious clinical-histological entity secondary to different diseases. Collapsing glomerulonephritis is a proliferative podocytopathy that usually has an unfavorable renal prognosis. We present a case in which both entities were associated, which is an infrequent form of hepatosplenic T-cell lymphoma. In addition, we review the role of the markers of podocyte dedifferentiation in this glomerulopathy and its pathophysiology and treatment.

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  • María Adoración Martín-Gómez Unidad de Nefrología, Hospital de Poniente, El Ejido, España
  • Mercedes Caba-Molina Servicio de Anatomía Patológica, Hospital San Cecilio, Granada, España
  • María José Viciana-Martínez-Lage Servicio de Anatomía Patológica, Hospital de Poniente, El Ejido, España
  • Rosa Ortega-Salas Servicio de Anatomía Patológica, Hospital Universitario Reina Sofía, Córdoba, España
  • Alicia Sánchez-Crespo Unidad de Hematología, Hospital de Poniente, El Ejido, España
  • Manuel Jesús Soriano-Pérez Servicio de Medicina Interna, Hospital de Poniente, El Ejido, España
  • Mercedes Gómez-Morales Servicio de Anatomía Patológica, Hospital San Cecilio, Granada, España

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How to Cite
1.
Martín-Gómez MA, Caba-Molina M, Viciana-Martínez-Lage MJ, Ortega-Salas R, Sánchez-Crespo A, Soriano-Pérez MJ, et al. Collapsing glomerulonephritis with podocyte markers in hemophagocytic syndrome secondary to hepatosplenic T-cell lymphoma. biomedica [Internet]. 2018 Dec. 1 [cited 2024 May 16];38(4):456-62. Available from: https://revistabiomedica.org/index.php/biomedica/article/view/3893
Published
2018-12-01
Issue
Vol. 38 No. 4 (2018)
Section
Case presentation

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