Seguimiento inmunológico después de trasplante renal: una propuesta para la práctica clínica en Colombia

Melissa Andrea Ortiz , Cristiam Mauricio Álvarez , Ana María Arrunátegui , Yazmin Rocío Arias , Adriana Villegas , .

Palabras clave: trasplante de riñón, isoanticuerpos, rechazo de injerto

Resumen

El daño del injerto es un proceso multifactorial que se inicia tempranamente después de la mayoría de los trasplantes de donantes sin HLA idéntico. Puede deberse a las comorbilidades del receptor, al estado del donante, al tiempo de isquemia, y al fenómeno de isquemia y reperfusión, entre otros, condiciones que inducen factores metabólicos e inmunológicos que finalmente desembocan en la disfunción del injerto. Sin embargo, entre el momento del trasplante y la aparición de los signos y síntomas existe un periodo que puede tardar semanas o años. Por ello, después del trasplante renal, es importante hacer un seguimiento racional que incluya la evaluación clínica y permita anticiparse al daño inmunológico del injerto. En este ensayo se propone un algoritmo de seguimiento del injerto renal después del trasplante.

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Cómo citar
1.
Ortiz MA, Álvarez CM, Arrunátegui AM, Arias YR, Villegas A. Seguimiento inmunológico después de trasplante renal: una propuesta para la práctica clínica en Colombia. biomedica [Internet]. 1 de septiembre de 2020 [citado 31 de octubre de 2020];40(3):479-86. Disponible en: https://revistabiomedica.org/index.php/biomedica/article/view/5092
Publicado
2020-09-01
Sección
Ensayo