Screening for Chagas disease in blood banks
Keywords:
blood banks, Trypanosoma cruzi, Chagas disease, Colombia
Abstract
The screening programs for the Chagas disease agent, Trypanosoma cruzi, were examined in Colombian blood banks and, as a consequence, several procedural improvements in the blood bank network were recommended. Screening strategies and techniques were examined, as well as the action taken when seropositive donors were discovered. From a total of 180 blood banks in 33 departments, 103 banks in 20 departments answered the survey. The 103 banks collected 291,105 units of blood, corresponding to 66.6% of all units collected in the country in 1997. Of these blood units, 99.6% were screened for Chagas trypanosomes; 3,321 (1.2%) of 287,048 were found positive for anti-T. cruzi. The data were grouped by department; geographical differences for seroprevalence rates varied markedly between 0% and 12.6%. The most commonly used serological technique was ELISA, but only 33.2% of the positive samples for anti-T. cruzi underwent further confirmatory testing, mainly through indirect immunofluorescent test. Most (95.1%) of the blood banks used basic, internal quality control procedures, and 73.8% sent positive samples to other laboratories for external quality control.Downloads
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How to Cite
1.
Behrend M, Beltrán M, Restrepo M, Kroeger A. Screening for Chagas disease in blood banks. biomedica [Internet]. 2002 Mar. 1 [cited 2024 May 19];22(1):39-45. Available from: https://revistabiomedica.org/index.php/biomedica/article/view/1138
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Published
2002-03-01
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Original articles
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