Efficacy of ivermectin in the treatment of children parasitized by Strongyloides stercoralis.
Keywords:
Strongyloides stercoralis, strongyloidiasis, ivermectin, intestinal parasites
Abstract
In a small village of Amazonian Colombia, the efficacy of ivermectin (200 microg/kg/day) was determined in a two-day treatment of children with uncomplicated strongyloidiasis. Criteria for inclusion in the study were as follows: absence of acute disease, no pretreatment with antiparasitic drugs within the last month, absence of severe liver or neurological disorders, and at least 2 of 4 stool samples positive for Strongyloides stercoralis. The Baermann technique was used to detect larvae; it had the advantage of reducing the frequency of false negative results in the subsequent examinations. Of 60 potential subjects, 49 fulfilled the above criteria. The cure rate for the S. stercoralis infection was 94% (46/49), with slight and temporary side effects. The effects of ivermectin on other intestinal parasites were characterized as well. In conclusion, a 200 microg/kg/d ivermectin dose was an adequate therapeutic regimen in the treatment of uncomplicated strongyloidiasis in children.Downloads
Download data is not yet available.
How to Cite
1.
Ordóñez LE, Angulo ES. Efficacy of ivermectin in the treatment of children parasitized by Strongyloides stercoralis. Biomed. [Internet]. 2004 Mar. 1 [cited 2024 Jul. 27];24(1):33-41. Available from: https://revistabiomedica.org/index.php/biomedica/article/view/1246
Some similar items:
- María Isabel Giraldo, Nora Lizeth García, Jhon Carlos Castaño, Prevalence of intestinal helminths in dogs from Quindío Province. , Biomedica: Vol. 25 No. 3 (2005)
- Elba G. Rodríguez-Pérez, Alma Y. Arce-Mendoza, Roberto Saldívar-Palacios, Kevin Escandón-Vargas, Fatal Strongyloides stercoralis hyperinfection syndrome in an alcoholic diabetic patient from México , Biomedica: Vol. 40 No. Supl. 1 (2020): Mayo, Infecciones en el trópico
- Nilo Manoel Pereira Vieira Barreto , Marina Morena Brito Farias , Cíntia de Lima Oliveira, Weslei Almeida Costa Araujo , Maria Fernanda Rios Grassi , Joelma Nascimento de Souza , Beatriz Soares Jacobina , Márcia Cristina Aquino Teixeira, Bernardo Galvão-Castro, Neci Matos Soares, Evaluation of Strongyloides stercoralis infection in patients with HTLV-1 , Biomedica: Vol. 42 No. 1 (2022)
- Jorge Alberto García-Aguilar, Jackeline Alger, Frequency of strongyloidiasis and associated factors: Analysis of 13 years of laboratory results in a tertiary referral hospital in Honduras, 2010-2022 , Biomedica: Vol. 43 No. 4 (2023)
Published
2004-03-01
Issue
Section
Original articles
Article metrics | |
---|---|
Abstract views | |
Galley vies | |
PDF Views | |
HTML views | |
Other views |