Positive 14-3-3 and tau proteins in a sporadic Creutzfeldt-Jakob disease case and a brief perspective of prion diseases in Colombia

Kevin Escandón-Vargas, Andrés Zorrilla-Vaca, Raúl Heli Corral-Prado, .

Keywords: Creutzfeldt-Jakob syndrome, prions, case reports

Abstract

Prion diseases are rare neurodegenerative disorders occurring worldwide and affecting both humans and animals. Herein, we present the case of a patient diagnosed with definite sporadic Creutzfeldt-Jakob disease in Cali, Colombia. Besides neurological examination, 14-3-3 and tau proteins were valuable tools supporting the diagnosis. We also present a brief perspective of the prion diseases reported in Colombia to date. Although the incidence of prion diseases is unknown in Colombia, our literature review revealed that one case of scrapie in 1981 and 29 human sporadic cases of Creutzfeldt-Jakob disease have been documented and published in our country.

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  • Kevin Escandón-Vargas Escuela de Medicina, Facultad de Salud, Universidad del Valle, Cali, Colombia
  • Andrés Zorrilla-Vaca Escuela de Medicina, Facultad de Salud, Universidad del Valle, Cali, Colombia
  • Raúl Heli Corral-Prado Escuela de Medicina, Facultad de Salud, Universidad del Valle, Cali, Colombia

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How to Cite
1.
Escandón-Vargas K, Zorrilla-Vaca A, Corral-Prado RH. Positive 14-3-3 and tau proteins in a sporadic Creutzfeldt-Jakob disease case and a brief perspective of prion diseases in Colombia. biomedica [Internet]. 2016 Apr. 1 [cited 2024 May 17];36(Sup1):29-36. Available from: https://revistabiomedica.org/index.php/biomedica/article/view/2729

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Published
2016-04-01

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