Detection of Chlamydia trachomatis infection in sexually active women in Venezuela

Milagros Joya , Ricardo Heredia , Daniel Bastidas, Gilberto Bastidas , .

Keywords: Chlamydia trachomatis, infection, immunoglobulin M, immunoglobulin G, chain reaction polymerase, epidemiology

Abstract

Introduction: Genital Chlamydia trachomatis infection is one of the most frequent in the world; about 85 million new cases of this pathology are registered each year, which causes severe complications in women and newborns.
Objective: To determine the clinical-epidemiological characteristics of C. trachomatis infection in sexually active Venezuelan women.
Materials and methods: Descriptive, cross-sectional, and field study based on the clinical history and physical examination, detection of infection with immunoenzymatic assay with anti-LPS polyclonal antibody and confirmation of results with molecular biology test. The sample consisted of 100 sexually active women over 12 years of age from Carabobo state, Venezuela.
Results: The women were mostly between 20 and 45 years old, in 25% of them IgG antibodies to C. trachomatis were detected and in 84% of these the infection was confirmed by PCR, in none of the women IgM antibodies to C. trachomatis were found.
Conclusion: Chronic infection characterizes women between 20 and 45 years of age; the immunoenzymatic test yielded false positives corroborated by PCR.

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How to Cite
1.
Joya M, Heredia R, Bastidas D, Bastidas G. Detection of Chlamydia trachomatis infection in sexually active women in Venezuela. biomedica [Internet]. 2022 Sep. 2 [cited 2024 May 18];42(3):522-30. Available from: https://revistabiomedica.org/index.php/biomedica/article/view/6246

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Published
2022-09-02
Section
Short communication

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