Modification of a Radiometric Microtest to detect Plasmodium falciparum Resistance to Several Drugs
Keywords:
Plasmodium falciparum, resistance, in vitro tests, anti-malaric drugs
Abstract
The development of strategies to control malaria requires precise knowledge about the drug-resistant parasite levels and geographical distribution. Unfortunately currently available methods are not fully adequate for these parameters to be established. This paper describes the improvement of a radiometric micro-test to detect resistance to several drugs. This test is easy, rapid and permits analysis of numerous samples in a short time. A molecular assay is not currently available for the determination of resistance because the molecular mechanisms behind chloroquine, amodiaquine, mefloquine, quinine or halofantrine resistance remain obscure. Under these circumstances, we recommend the use of the modified microtest for them.Downloads
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How to Cite
1.
Chaparro J, Wasserrnanz M. Modification of a Radiometric Microtest to detect Plasmodium falciparum Resistance to Several Drugs. biomedica [Internet]. 1999 Mar. 1 [cited 2024 May 18];19(1):25-34. Available from: https://revistabiomedica.org/index.php/biomedica/article/view/1004
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Published
1999-03-01
Issue
Section
Original articles
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