Wernicke-Korsakoff syndrome secondary to cytomegalovirus encephalitis: A case report

Luis Guillermo Uribe, María Alejandra Pérez, Camilo Andrés Lara, Natalia Rueda, Javier Augusto Hernández, .

Keywords: Encephalitis, viral, cytomegalovirus, Korsakoff syndrome, Wernicke encephalopathy, infectious encephalitis, cytomegalovirus infections

Abstract

Cytomegalovirus (CMV) is one of the opportunistic microorganisms with the highest prevalence in immunocompromised patients. Reactivation has decreased after the introduction of highly active antiretroviral therapy (HAART). Encephalitis has been reported in the coinfection as one of the most frequent presentations.
We present the case of a young adult patient with HIV infection and rapid neurological deterioration due to classic clinical symptoms and signs of the Wernicke-Korsakoff syndrome, with no risk factors for thiamine deficiency, with images by nuclear magnetic resonance typical of the syndrome, and identification of cytomegalovirus in cerebrospinal fluid. The specific treatment for CMV managed to control the symptoms with neurological sequelae in progression towards improvement.
This is one of the few cases reported in the literature of Wernicke syndrome secondary to cytomegalovirus encephalitis.

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  • Luis Guillermo Uribe Departamento de Infectología, Hospital Universitario de Bucaramanga “Los Comuneros”, Bucaramanga, Colombia
  • María Alejandra Pérez Medicina General, Hospital Universitario de Bucaramanga “Los Comuneros”, Bucaramanga, Colombia
  • Camilo Andrés Lara Radiología IDIME, Hospital Universitario de Bucaramanga “Los Comuneros”, Bucaramanga, Colombia
  • Natalia Rueda Medicina General, Hospital Universitario de Bucaramanga “Los Comuneros”, Bucaramanga, Colombia
  • Javier Augusto Hernández Medicina General, Hospital Universitario de Bucaramanga “Los Comuneros”, Bucaramanga, Colombia

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How to Cite
1.
Uribe LG, Pérez MA, Lara CA, Rueda N, Hernández JA. Wernicke-Korsakoff syndrome secondary to cytomegalovirus encephalitis: A case report. biomedica [Internet]. 2017 Dec. 1 [cited 2024 May 17];37(4):444-51. Available from: https://revistabiomedica.org/index.php/biomedica/article/view/3451

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Published
2017-12-01
Section
Case presentation

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