Fatal Strongyloides stercoralis hyperinfection syndrome in an alcoholic diabetic patient from México
Abstract
Strongyloides stercoralis hyperinfection syndrome is a medical emergency that requires a high level of suspicion. Immunocompromised patients are at high risk of hyperinfection syndrome; however, malnutrition, alcoholism, and diabetes mellitus also need to be considered as predisposing factors. The diagnosis and treatment of Strongyloides hyperinfection are challenging and patients often have severe complications. Consequently, mortality is overwhelmingly high, with proportions above 60%.
Herein, we report a case of Strongyloides hyperinfection in a 40-year-old alcoholic diabetic patient living in México. Unfortunately, the late diagnosis resulted in his death despite the treatment and supportive measures. Increased awareness is needed to prevent the dire consequences of strongyloidiasis.
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References
Olsen A, van Lieshout L, Marti H, Polderman T, Polman K, Steinmann P, et al. Strongyloidiasis – the most neglected of the neglected tropical diseases? Trans R Soc Trop Med Hyg. 2009;103:967-72. https://doi.org/10.1016/j.trstmh.2009.02.013
Bisoffi Z, Buonfrate D, Montresor A, Requena-Méndez A, Muñoz J, Krolewiecki AJ, et al. Strongyloides stercoralis: A plea for action. PLoS Negl Trop Dis. 2013;7:7-10. https://doi.org/10.1371/journal.pntd.0002214
Guarner J, Matilde-Nava T, Villaseñor-Flores R, Sánchez-Mejorada G. Frequency of intestinal parasites in adult cancer patients in México. Arch Med Res. 1997;28:219-22.
Faulkner CT, Borrego-García B, Logan MH, New JC, Patton S. Prevalence of endoparasitic infection in children and its relation with cholera prevention efforts in México. Rev Panam Salud Pública. 2003;14:31-41. https://doi.org/10.1590/S1020-49892003000600006
Carrada-Bravo T. Strongyloides stercoralis: ciclo vital, cuadros clínicos, epidemiología, patología y terapéutica. Revista Latinoamericana de Patología Clínica y Medicina de Laboratorio. 2008;55:88-110.
Viney ME, Lok JB. The biology of Strongyloides spp. Pasadena: WormBook; 2015. p. 1-17. https://doi.org/10.1895/wormbook.1.141.2
Krolewiecki A, Nutman TB. Strongyloidiasis. Infect Dis Clin North Am. 2019;33:135-51. https://doi.org/10.1016/j.idc.2018.10.006
Teixeira MCA, Pacheco FTF, Souza JN, Silva MLS, Inês EJ, Soares NM. Strongyloides stercoralis infection in alcoholic patients. Biomed Res Int. 2016;2016:4872473. https://doi.org/10.1155/2016/4872473
McGuire E, Welch C, Melzer M. Is Strongyloides seropositivity associated with diabetes mellitus? A retrospective case-control study in an East London NHS Trust. Trans R Soc Trop Med Hyg. 2019;113:189-94. https://doi.org/10.1093/trstmh/try132
Silva MLS, de J. Inês E, da S. Souza AB, dos S. Dias VM, Guimarães CM, Menezes ER, et al. Association between Strongyloides stercoralis infection and cortisol secretion in alcoholic patients. Acta Trop. 2016;154:133-8. https://doi.org/10.1016/j.actatropica.2015.11.010
Buonfrate D, Requena-Méndez A, Angheben A, Muñoz J, Gobbi F, van Den Ende J, et al. Severe strongyloidiasis: A systematic review of case reports. BMC Infect Dis. 2013;13:78. https://doi.org/10.1186/1471-2334-13-78
Geri G, Rabbat A, Mayaux J, Zafrani L, Chalumeau-Lemoine L, Guidet B, et al. Strongyloides stercoralis hyperinfection syndrome: A case series and a review of the literature. Infection. 2015;43:691-8. https://doi.org/10.1007/s15010-015-0799-1
Henríquez-Camacho C, Gotuzzo E, Echevarría J, White AC, Terashima A, Samalvides F, et al. Ivermectin versus albendazole or thiabendazole for Strongyloides stercoralis infection. Cochrane Database Syst Rev. 2016;CD007745. https://doi.org/10.1002/14651858.CD007745.pub3
Barrett J, Broderick C, Soulsby H, Wade P, Newsholme W. Subcutaneous ivermectin use in the treatment of severe Strongyloides stercoralis infection: Two case reports and a discussion of the literature. J Antimicrob Chemother. 2016;71:220-5. https://doi.org/10.1093/jac/dkv315
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