Nutritional status in pediatric patients with predominant antibody deficiency

Abstract

Introduction. Predominant antibody deficiency is the most frequent group of inborn errors of immunity, but despite this, there is little information about their nutritional status.
Objective. To characterize the nutritional status of Colombian patients with predominant antibody deficiencies.
Material and methods. We analyzed clinical charts of patients with predominant antibody deficiency in a pediatric hospital in Bogota.
Results. 55 clinical histories were analyzed, the most frequent diagnoses were specific deficiency of polysaccharide antibodies, specific IgA deficiency, common variable immunodeficiency and agammaglobulinemia. More than 70% of the patients had sinopulmonary infections, the most frequent being pneumonia, followed by otitis and sinusitis. In children under 5 years of age, 45% had adequate weight for height, 18% risk of malnutrition and 18% moderate acute malnutrition, 4.5% had obesity, 4.5% were overweight, and 9% had a risk of being overweight. In those older than 5 years, 54% had an adequate body mass index, 22.5% were overweight, 9.6% were at risk of thinness, and 9.6% were thin. We found that the risk of short stature and short stature were more frequent than normal height in these patients, and present short stature percentages above those reported at the national level.
Conclusions. Due to the epidemic of childhood obesity, it will be more frequent to find overweight or obesity in children above 5 years, but it is more frequent to find short stature, for what we consider could be a more sensitive alarm sign for predominant antibody deficiency.