Autoimmune encephalitis associated to antibodies against the N-methyl-D-aspartate receptor: Report of two cases

José Bustos, Yasmin Sánchez, Jhon Medina, Rommy Olivieri, Julián Mojica, Johan Ortiz, .

Keywords: Encephalitis, receptors, glutamate, N-methylaspartate, autoimmunity, immunotherapy, antibodies

Abstract

Anti-N-methyl-D-aspartate receptor encephalitis is a neurological syndrome that is more common in young women and is often associated with ovarian teratoma. It is characterized by acute general unspecific symptoms that evolve to neurological deterioration, psychosis and seizures. In its more advanced stage it is associated with abnormal movements and dysautonomia.
We report two cases in women of 23 and 12 years of age. Given its low incidence, we present the clinical exercise that led to their diagnoses and the treatment options employed.

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  • José Bustos Departamento de Neurología, Hospital San Rafael, Tunja, Colombia Escuela de Medicina, Facultad de Ciencias de la Salud, Hospital San Rafael, Tunja, Colombia http://orcid.org/0000-0003-3863-5522
    Departamento de Neurología, Hospital San Rafael de Tunja
  • Yasmin Sánchez Escuela de Medicina, Facultad de Ciencias de la Salud, Hospital San Rafael, Tunja, Colombia Departamento de Neurología Pediátrica, Hospital San Rafael, Tunja, Colombia
  • Jhon Medina Escuela de Medicina, Facultad de Ciencias de la Salud, Hospital San Rafael, Tunja, Colombia
  • Rommy Olivieri Escuela de Medicina, Facultad de Ciencias de la Salud, Hospital San Rafael, Tunja, Colombia
  • Julián Mojica Escuela de Medicina, Facultad de Ciencias de la Salud, Hospital San Rafael, Tunja, Colombia
  • Johan Ortiz Escuela de Medicina, Facultad de Ciencias de la Salud, Hospital San Rafael, Tunja, Colombia

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How to Cite
1.
Bustos J, Sánchez Y, Medina J, Olivieri R, Mojica J, Ortiz J. Autoimmune encephalitis associated to antibodies against the N-methyl-D-aspartate receptor: Report of two cases. biomedica [Internet]. 2017 Apr. 1 [cited 2024 May 18];37(Sup.1):20-5. Available from: https://revistabiomedica.org/index.php/biomedica/article/view/2909

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Published
2017-04-01

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