Molecular biomarkers to assess health risks due to environmental contaminants exposure
Abstract
Biomarkers, or bioindicators, are metric tools that, when compared with reference values, allow specialists to perform risk assessments and provide objective information to decision makers to design effective strategies to solve health or environmental problems by efficiently using the resources assigned. Health risk assessment is a multidisciplinary exercise, and molecular biology is a discipline that greatly contributes to these evaluations because the genome, transcriptome, proteome and metabolome could be affected by xenobiotics causing measurable changes that might be useful biomarkers. Such changes may greatly depend on individual genetic background; therefore, the polymorphic distribution of exposed populations becomes an essential feature for adequate data interpretation. The aim of this paper is to offer an up-to-date review of the role of different molecular biomarkers in health risk assessments.
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References
Monath TP. Yellow fever. The arboviruses: Epidemiology and ecology. In: Monath TP, editor. Boca Ratón (FL): CRC Press; 1989. p. 139-231.
Simmons CP, Farrar JJ, Chau NV, Wills B. Dengue. N Engl J Med. 2012;366:1423-32. http://dx.doi.org/10.1056/nejmra1110265
Pialoux G, Gauzere BA, Jaureguiberry S, Strobel M. Chikungunya, an epidemic arbovirosis. Lancet Infect Dis. 2007;5:319-27. http://dx.doi.org/10.1016/s1473-3099(07)70107-x
Marchette NJ, García R, Rudnick A. Isolation of Zika virus from Aedes aegypti mosquitoes in Malaysia. Am J Trop Med Hyg. 1969;18:411-5.
Mattingly PF. Genetical aspects of the Aedes aegypti problem I. Taxonomy and bionomics. Ann Trop Med Parasit. 1957;51:392-408.
Tabachnick WJ, Munstermann LE, Powell JR. Genetic distinctness of sympatric forms of Aedes aegypti in East Africa. Evolution. 1979;33:287-95. http://dx.doi.org/10.2307/2407619
Brown JE, Evans BR, Zheng W, Obas V, Barrera-Martínez L, Egizi A, et al . Human impacts have shaped historical and recent evolution in Aedes aegypti , the dengue and yellow fever mosquito. Evolution. 2014;68:514-25. http://dx.doi.org/10.1111/evo.12281
Petersen JL. Behavior differences in two subspecies of Aedes aegypti (L.) (Diptera: Culicidae) in East Africa (Dissertation). Notre Dame, IN: University of Notre Dame; 1977.
Lounibos LP. Invasions by insect vectors of human disease. Annu Rev Entomol. 2002;47:233-66. http://dx.doi.org/10.1146/annurev.ento.47.091201.145206
Kraemer MU, Sinka ME, Duda KA, Mylne QN, Shearer MF, Barker MC , et al . The global distribution of the arbovirus vectors Aedes aegypti and Ae. albopictus . Elife. 2015;4:e08347. http://dx.doi.org/10.7554/eLife.08347
Dhimal M, Gautam I, Joshi HD, O´Hara RB, Ahrens B, Kuch U. Risk factors for the presence of chikungunya and dengue vectors ( Aedes aegypti and Aedes albopictus ), their altitudinal distribution and climatic determinants of their abundance in Central Nepal. PLoS Negl Trop Dis . 2015:9;e0003545. http://doi.org/10.1371/journal.pntd.0003545
Ibáñez-Bernal S. Nuevo registro altitudinal de Aedes ( Stegomyia ) aegypti (Linnaeus, 1762) (Diptera: Culicidae) en México. Folia Entomol Mex. 1987;72:163-164.
Lozano-Fuentes S, Hayden MH, Welsh-Rodríguez C, Ochoa-Martínez C, Tapia-Santos B, Kobylinski CK, et al . The dengue virus mosquito vector Aedes aegypti at high elevation in México. Am J Trop Med Hyg. 2012;87:902-9. http://dx.doi.org/10.4269/ajtmh.2012.12-0244
Navarro JC, Ventura FD, Zorrilla A, Liria J. Registros de mayor altitud para mosquitos (Diptera: Culicidae) en Venezuela. Rev Biol Trop. 2010;58:245-54. http://dx.doi.org/10.15517/rbt.v58i1.5206
Suárez FM, Nelson JM. Registro de altitud del Aedes aegypti en Colombia. Biomédica. 1981;1:225. http://dx.doi.org/10.7705/biomedica.v1i4.1809
Kuno G. Universal diagnostic RT-PCR protocol for arboviruses. J Virol Methods. 1998;72:27-41. http://dx.doi.org/10.1016/s0166-0934(98)00003-2
Ruiz-López F. Molecular systematics of the Oswaldoi complex ( Anopheles ; Nyssorhynchus ) in South America. Dissertation. London: University of Kent and The Natural History Museum; 2010.
Rodríguez H, De la Hoz F. Dengue and dengue and vector behaviour in Cáqueza, Colombia, 2004. Rev Salud Pública. 2005;7:1-15. http://dx.doi.org/10.1590/s0124-00642005000100001
Padilla JC, Rojas DP, S a� enz-G o� mez R. Dengue en Colombia: epidemiología de la reemergencia a la hiper-endemia. Bogotá: Guías de Impresión, Ltda.; 2012. p. 249.
Herrera-Basto E, Prevots DR, Zárate ML, Silva JL, Sepúlveda-Amor J. First reported outbreak of classical dengue fever at 1,700 meters above sea level in Guerrero State, México, June 1988. Am J Trop Med Hyg. 1992;46:649-53.
Hales S, Wet N, Maindonald J, Woodward A. Potential effect of population and climate changes on global distribution of dengue fever: An empirical model. Lancet. 2002;360:830-4. http://dx.doi.org/10.1016/S0140-6736(02)09964-6
Khormi HM, Kumar L. Climate change and the potential global distribution of Aedes aegypti : Spatial modelling using GIS and CLIMEX. Geospat Health. 2014;8:405-15. http://dx.doi.org/10.4081/gh.2014.29
Cassab A, Morales V, Máttar S. Factores climáticos y casos de dengue en Montería, Colombia. 2003-2008. Rev Salud Pública. 2011;13:115-28. http://dx.doi.org/10.1590/s0124-00642011000100010
Rúa-Uribe G, Calle D, Rojo R, Henao E, Sanabria W, Suárez C. Influencia del evento climático El Niño sobre la dinámica de transmisión de dengue en Medellín, Antioquia-Colombia. Iatreia. 2012;25:314-22.
Rúa-Uribe GL, Suárez-Acosta C, Chauca J, Ventosilla P, Almanza R. Modelado del efecto de la variabilidad climática local sobre la transmisión de dengue en Medellín (Colombia) mediante análisis de series temporales. Biomédica. 2013; 142-52. http://dx.doi.org/10.7705/biomedica.v33i0.1444
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