Reporting of statistical regression analyses in Biomédica: A critical assessment review

Julián Alfredo Fernández-Niño, Rosa Ivonne Hernández-Montes, Laura Andrea Rodríguez-Villamizar, .

Keywords: Biostatistics, data analysis, regression analysis, bias (epidemiology), Colombia

Abstract

Introduction: Regression modeling is a statistical method commonly used in health research, especially by observational studies.
Objective: The objectives of this paper were to 1) determine the frequency of reporting of regression modeling in original biomedical and public health articles that were published in Biomédica between 2000 and 2017; 2) describe the parameters used in the statistical models, and 3) describe the quality of the information reported by the studies to explain the statistical analyses.
Materials and methods: We conducted a critical assessment review of all original articles published in Biomédica between 2000 and 2017 that used regression models for the statistical analysis of the studies main objectives. We generated a 20-item checklist based on four good practice guidelines for the presentation of statistical methods.
Results: Most of the studies were observational studies related to public health sciences (65.7%). Less than half (37.2%) of them reported using a combination of conceptual frameworks and statistical criteria for the selection of variables to be included in the regression model. Less than one quarter (22.1%) reported the verification of the assumptions of the model. The most frequently used uncertainty measure was the p-value (73.5%).
Conclusion: There are significant limitations in the quality of the reports of statistical regression models, which reviewers and readers need in order to correctly assess and interpret the statistical models. The results, herein, are provided as an invitation to researchers, reviewers, and editors of biomedical journals to develop, promote, and control an appropriate culture for statistical analysis and reporting in Colombia.

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  • Julián Alfredo Fernández-Niño Departamento de Salud Pública, Facultad de Salud, Universidad Industrial de Santander, Bucaramanga, Colombia
  • Rosa Ivonne Hernández-Montes Escuela de Salud Pública de México, Instituto Nacional de Salud Pública, Cuernavaca, México
  • Laura Andrea Rodríguez-Villamizar Departamento de Salud Pública, Facultad de Salud, Universidad Industrial de Santander, Bucaramanga, Colombia

References

Jenicek M. Epidemiology, evidenced-based medicine, and evidence-based public health. J Epidemiol. 1997;7:187-97. https://doi.org/10.2188/jea.7.187

Tang JL, Griffiths S. Review paper: epidemiology, evidencebased medicine, and public health. Asia Pac J Public Health. 2009;21:244-51. https://doi.org/10.1177/1010539509335516

Burns PB, Rohrich RJ, Chung KC. The levels of evidence and their role in evidence-based medicine. Plast Reconstr Surg. 2011;128:305-10. https://doi.org/10.1097/PRS.0b013e318219c171

Ryan T. Modern Regression Methods. 2nd ed. Hoboken, N.J.: Wiley; 2009. p. 672.

Lang T, Altman D. Basic statistical reporting for articles published in clinical medical journals: the SAMPL guidelines. In: Smart P, Maisonneuve H, Polderman A, editors. Science Editors’ Handbook. London: European Association of Science Editors; 2013.

Departamento Administrativo Nacional de Ciencia y Tecnología COLCIENCIAS. Publindex. Fecha de consulta: 12 de octubre de 2016. Disponible en: http://scienti.colciencias.gov.co:8084/publindex/

Bailar J, Mosteller F. La información estadística que deben proporcionar los artículos publicados en revistas médicas. Salud Públ Méx. 1992;34:103-15.

Kearns B, Ara R, Wailoo A, Manca A, Alava MH, Abrams K, et al. Good practice guidelines for the use of statistical regression models in economic evaluations. Pharmacoeconomics. 2013;31:643-52. https://doi.org/10.1007/s40273-013-0069-y

Núñez E, Steyerberg E, Núñez J. Estrategias para la elaboración de modelos estadísticos de regresión. Rev Esp Cardiol. 2011;64:501-7. https://doi.org/10.1016/j.recesp.2011.01.019

Gómez LA, Nicholls RS. Avances en visibilidad, acceso y reconocimiento internacional de la revista Biomédica. Biomédica. 2008;28:5-6.

Idrovo AJ, Fernandez-Nino JA, Bojorquez-Chapela I, Ruiz-Rodriguez M, Agudelo CA, Pacheco OE, et al. Perception of epidemiological competencies by public health students in Mexico and Colombia during the influenza A (H1N1) epidemic. Rev Panam Salud Publica. 2011;30:361-9. https://doi.org/10.1590/S1020-49892011001000010

Fernandez-Nino JA, Trejo-Valdivia B. Costumbres, mal uso y abuso en estadística. Rev Univ Ind Santander Salud. 2016;48:5-6.

Lu CY. Observational studies: a review of study designs, challenges and strategies to reduce confounding. Int J Clin Pract. 2009;63:691-7. https://doi.org/10.1111/j.1742-1241.2009.02056.x

Whittingham M, Stephens P, Bradbury R, Freckleton R. Why do we still use stepwise modelling in ecology and behaviour? J Anim Ecol. 2006;75:1182-9. https://doi.org/10.1111/j.1365-2656.2006.01141.x

Walter S, Tiemeier H. Variable selection: current practice in epidemiological studies. Eur J Epidemiol. 2009;24:733-6. https://doi.org/10.1007/s10654-009-9411-2

Goff L. The bias from misspecification of control variables as linear. 2014. Fecha de consulta: 12 de octubre de 2016. Disponible en: http://www.rff.org/files/sharepoint/WorkImages/Download/RFF-DP-14-41.pdf

Rao P. Some notes on misspecification in multiple regressions. The American Statistician. 1971;25:37-9.

Ramsey JB. Test for specification errors in classical linear least-squares regression analysis. The Journal of the Royal Society Series B (Methodological). 1969;31:350-71.

Hall S, Asteriou D. Applied Econometrics. 2nd edition. New York: Palgrave Macmillan; 2011.

How to Cite
1.
Fernández-Niño JA, Hernández-Montes RI, Rodríguez-Villamizar LA. Reporting of statistical regression analyses in Biomédica: A critical assessment review. biomedica [Internet]. 2018 Jun. 15 [cited 2024 May 18];38(2):173-9. Available from: https://revistabiomedica.org/index.php/biomedica/article/view/3648

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Published
2018-06-15
Section
Original articles

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