Outbreak report of SARS-CoV-2 infection by airborne transmission: Epidemiologic and molecular evidence

María-Cristina Navas , Juan D. Cerón, Wbeimar Aguilar-Jiménez , María T. Rugeles, Francisco J. Díaz , .

Keywords: SARS-CoV-2, COVID-19, disease outbreaks, vaccination, Colombia

Abstract

Introduction: It has been shown that the transmission of SARS-CoV-2 occurs mainly by air, and the risk of infection is greater in closed spaces.
Objective: To describe the epidemiology, virology and molecular characterization of a COVID-19 outbreak at a closed vaccination point during the third wave of SARS-CoV-2 in Colombia.
Materials and methods: Diagnostic tests, interviews, sampling, cell cultures and viral sequencing were carried out, the latter being molecular characterization and lineage identification.
Results: Seven workers were positive for SARS-CoV-2; among these, 3 samples were analyzed, plus an additional sample belonging to the mother of the presumed index
case; all samples were identified with lineage B.1.625, with a maximum of 2 nucleotides difference between them.
Conclusions: Variant B.1.625 was identified as the cause of the COVID-19 outbreak, and a co-worker was also identified as the index case. Unexpectedly, attending a vaccination day became a risk factor for acquiring the infection.

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How to Cite
1.
Navas M-C, Cerón JD, Aguilar-Jiménez W, Rugeles MT, Díaz FJ. Outbreak report of SARS-CoV-2 infection by airborne transmission: Epidemiologic and molecular evidence. biomedica [Internet]. 2023 Mar. 30 [cited 2024 May 11];43(1):121-30. Available from: https://revistabiomedica.org/index.php/biomedica/article/view/6695

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Published
2023-03-30
Section
Original articles

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