Molecular surveillance of invasive penicillin-resistant Streptococcus pneumoniae Colombian isolates recovered from children less than 5 years of age.

Jaime Moreno, Vienvilay Phandanouvong, Elizabeth Castañeda, .

Keywords: Streptococcus pneumoniae, diminished susceptibility to penicillin, PFGE, clone, genetic relatedness

Abstract

The rapid increase of penicillin-resistant Streptococcus pneumoniae isolates could be a consequence of the spread of clones or due to the antimicrobial selective pressure. The genetic relatedness of 190 invasive isolates S. pneumoniae with reduced susceptibility to penicillin recovered from Colombian children less than 5 years old during a surveillance study from 2000 to 2003 was determined by the use of pulsed-field electrophoresis (PFGE). Overall, 42 different PFGE patterns were identified, but 4 of them included 76% of all isolates. They were related with international clones 1-Spain23F, 2-Spain6B, 3-Spain9V and 26-Colombia23F. Our results indicated that the dissemination of penicillin-resistant S. pneumoniae was the result of the spread of international clones, specially, the 3-Spain9V clone.

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  • Jaime Moreno Grupo de Microbiología, Instituto Nacional de Salud, Bogotá, DC, Colombia.
  • Vienvilay Phandanouvong Grupo de Microbiología, Instituto Nacional de Salud, Bogotá, D.C.
  • Elizabeth Castañeda Grupo de Microbiología, Instituto Nacional de Salud, Bogotá, D.C.
How to Cite
1.
Moreno J, Phandanouvong V, Castañeda E. Molecular surveillance of invasive penicillin-resistant Streptococcus pneumoniae Colombian isolates recovered from children less than 5 years of age. biomedica [Internet]. 2004 Sep. 1 [cited 2024 May 19];24(3):296-301. Available from: https://revistabiomedica.org/index.php/biomedica/article/view/1276

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Published
2004-09-01
Section
Short communication

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