Adverse reproductive outcomes among women working in Colombian floriculture: a summary of the evidence through metaanalysis
Keywords:
pesticides/adverse effects, agriculture, abortion, spontaneous, infant/premature, metaanalysis, Colombia
Abstract
Introduction. Workers in floriculture are exposed to pesticides and other risk factors. Work in these occupational environments is suspected to be associated with adverse reproductive outcomes. However, epidemiological studies in Colombia, a country that has a long tradition with this occupation, have not been consistent or conclusive.Objective. To quantify the effect of women's work in Colombian floriculture in the occurrence of spontaneous abortion, prematurity, and birth defects, using the results of two previous studies.
Material and methods. The results of two previous studies among Colombian floriculture worker populations were summarized with metaanalysis techniques. A critical evaluation of each of the studies identified potential biases and methodological limitations.
Results. The pooled estimator of spontaneous abortion was 2.24 (95CI: 1.87-2.68); that of premature infant birth was 1.49 (95%CI: 0.91-2.43), and of birth defects 1.31 (95%CI: 1.95-1.64).
Conclusions. The analyses suggested that work in floriculture is associated with a higher occurrence of spontaneous abortion and birth defects. However, these effects are not necessarily associated with pesticide exposure. Other risk factors requiring further study are levels of physical activity and high temperature in greenhouses. Data from countries which have initiated
occupations in floriculture more recently will add valuable evidence for this controversial association.
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References
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25. Walsh D, Downe S. Meta-synthesis method for qualitative research: A literature review. J Adv Nurs.
2005;50:204-11.
26. Idrovo AJ. Hacia una salud pública pluralista: el caso
de los plaguicidas y la salud humana. Rev Salud Pública
(Bogotá). 2005;7:349-59.
27. De León J. Situación de las floricultoras con exposición crónica a mezclas de plaguicidas en Morelos, México. Boletín Rapam. 1997;20:10-1.
28. Harari R. Seguridad, salud y ambiente en la floricultura. Quito: Corporación IFA; 2004.
exposure of carnation floriculturists in Bogotá, Colombia (Technical Report). Miami: University of Miami School of Medicine; 1983.
2. Barreto-Charry AV, Castiblanco-Rodríguez AL, Ospina de Nigrinis S, Idrovo AJ. Implementación y validación de una metodología analítica para la determinación de etilentiourea en orina y parches de extracción. Rev Colomb Cienc Quim Farm. 2003;32:51-7.
3. Varona ME, Tolosa JE, Cárdenas O, Torres CH, Pardo D, Carrasquilla G, et al. Descripción del uso y manejo de plaguicidas en las empresas de flores afiliadas a Asocolflores. Biomédica. 2005;25:377-89.
4. Restrepo M, Muñoz N, Day NE, Parra JE, de Romero L, Nguyen-Dinh X. Prevalence of adverse reproductive outcomes in a population occupationally exposed to pesticides in Colombia. Scand J Work Environ Health. 1990;16:232-8.
5. Restrepo M, Muñoz N, Day NE, Parra JE, Hernández CA, Blettner M, et al. Birth defects among children born to a population occupationally exposed to pesticides in Colombia. Scand J Work Environ Health. 1990;16:239-46.
6. Idrovo AJ, Sanín LH, Cole D, Chavarro J, Cáceres H, Narváez J, et al. Time to first pregnancy among women working in agricultural production. Int Arch Occup Environ Health. 2005;78:493-500.
7. Varona M, De la Hoz F, Peña G, Cárdenas O. Seguimiento de una cohorte de mujeres trabajadoras en cultivos de flores de la Sabana de Bogotá. Biomédica. 1998;18:30-6.
8. Varona M, Cárdenas O, Crane C, Rocha S, Cuervo G, Vargas J. Prevalencia de alteraciones citogenéticas en trabajadores expuestos a plaguicidas en empresas de flores de Bogotá, Colombia. Biomédica. 2003;23:141-52.
9. Hanke W, Jurewicz J. The risk of adverse reproductive and developmental disorders due to occupational pesticide exposure: an overview of current epidemiological evidence. Int J Occup Environ Health. 2004;17:223-43.
10. Sanborns M, Cole D, Kerr K, Vakil C, Sanín LH, Bassil K. Pesticide literature review. Toronto: The Ontario College of Family Physicians; 2004.
11. Idrovo AJ, Sanín LH, Cole DC. Tiempo para quedar en embarazo: consideraciones generales y metodológicas. Biomédica. 2005;25:398-411.
12. Kristensen P, Irgens LM. Maternal reproductive history: a registry based comparison of previous pregnancy
data derived from maternal recall and data obtained during the actual pregnancy. Acta Obstet Gynecol Scand. 2000;79:471-7.
13. Buka SL, Goldstein JM, Spartos E, Tsuang MT. The retrospective measurement of prenatal and perinatal events: accuracy of maternal recall. Schizophr Res. 2004;71:417-26.
14. Tomeo CA, Rich-Edwards JW, Michels KB, Berkey CS, Hunter DJ, Frazier AL, et al. Reproducibility and validity of maternal recall of pregnancy-related events.
Epidemiology. 1999;10:774-7.
15. Sanín-Aguirre LH, Restrepo M. Defectos al nacer y pesticidas en Colombia. En: Romieu I, Borja V, Hernández M, editores. Metodología epidemiológica aplicada a estudios de salud ambiental. Cuernavaca: Instituto Nacional de Salud Pública; 2000.p.59-73.
16. Armstrong BG. Effect of measurement error on epidemiological studies of environmental and occupational
exposures. Occup Environ Med. 1998;55:651-6.
17. Tooth L, Ware R, Bain C, Purdie DM, Dobson A. Quality of reporting of observational longitudinal research. Am J Epidemiol. 2005;161:280-8.
18. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986;7:177-88.
19. Hernández B, Velasco-Mondragón HE. Encuestas transversales. Salud Pública Mex. 2000;42:447-55.
20. Mann CJ. Observational research methods. Research design II: cohort, cross sectional, and case-control studies. Emerg Med J. 2003;20:54-60.
21. Weinberg CR, Wilcox AJ. Reproductive epidemiology. In: Rothman KJ, Greenland S, editors. Modern epidemiology.
2nd ed. Philadelphia: Lippincott-Raven Publishers; 1998.p.585-608.
22. Lacasaña M, Vázquez-Grameix H, Borja-Aburto VH, Blanco-Muñoz J, Romieu I, Aguilar-Garduño C, et al. Maternal and paternal occupational exposure to agricultural work and the risk of anencephaly. Occup
Environ Med. 2006;63:649-56.
23. Samet JM. What can we expect from epidemiologic studies of chemical mixtures? Toxicology. 1995;105:307-14.
24. Jurewicz J, Hanke W, Makowiec-Dabrowska T, Sobala W. Exposure to pesticides and heavy work in greenhouses during pregnancy: Does it affect birth weight? Int Arch Occup Environ Health. 2005;78:418-26.
25. Walsh D, Downe S. Meta-synthesis method for qualitative research: A literature review. J Adv Nurs.
2005;50:204-11.
26. Idrovo AJ. Hacia una salud pública pluralista: el caso
de los plaguicidas y la salud humana. Rev Salud Pública
(Bogotá). 2005;7:349-59.
27. De León J. Situación de las floricultoras con exposición crónica a mezclas de plaguicidas en Morelos, México. Boletín Rapam. 1997;20:10-1.
28. Harari R. Seguridad, salud y ambiente en la floricultura. Quito: Corporación IFA; 2004.
How to Cite
1.
Idrovo Álvaro J, Sanín LH. Adverse reproductive outcomes among women working in Colombian floriculture: a summary of the evidence through metaanalysis. biomedica [Internet]. 2007 Dec. 1 [cited 2024 May 16];27(4):490-7. Available from: https://revistabiomedica.org/index.php/biomedica/article/view/169
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Published
2007-12-01
Issue
Section
Original articles
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