Three cases of de novo multiple myeloma after kidney transplantation

John Fredy Nieto-Ríos, Mónica Zuluaga, Lina María Serna, Arbey Aristizábal, Catalina Ocampo-Kohn, Kenny Mauricio Gálvez, Adriana Alejandra Flórez, Gustavo Zuluaga, .

Keywords: multiple myeloma, kidney transplantation, kidney diseases, paraproteinemias

Abstract

Light chain-associated kidney compromise is frequent in patients with monoclonal gammopathies; it affects the glomeruli or the tubules, and its most common cause is multiple myeloma. It may develop after a kidney transplant due to recurrence of a preexisting multiple myeloma or it can be a de novo disease manifesting as graft dysfunction and proteinuria. A kidney biopsy is always necessary to confirm the diagnosis.
We describe three cases of kidney graft dysfunction due to multiple myeloma in patients without presence of the disease before the transplant.

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  • John Fredy Nieto-Ríos Unidad de Nefrología y Trasplante Renal, Hospital Pablo Tobón Uribe, Universidad de Antioquia, Medellín, Colombia
  • Mónica Zuluaga Facultad de Medicina Interna, Universidad Pontificia Bolivariana, Medellín, Colombia
  • Lina María Serna Unidad de Nefrología y Trasplante Renal, Hospital Pablo Tobón Uribe, Universidad de Antioquia, Medellín, Colombia
  • Arbey Aristizábal Unidad de Nefrología y Trasplante Renal, Hospital Pablo Tobón Uribe, Universidad de Antioquia, Medellín, Colombia
  • Catalina Ocampo-Kohn Unidad de Nefrología y Trasplante Renal, Hospital Pablo Tobón Uribe, Universidad de Antioquia, Medellín, Colombia
  • Kenny Mauricio Gálvez Unidad de Hematología y Oncología, Hospital Pablo Tobón Uribe, Medellín, Colombia
  • Adriana Alejandra Flórez Departamento de Patóloga Anatómica y Clínica, Hospital Universitario Fundación Santa Fe de Bogotá, Universidad de los Andes, Bogotá, D.C., Colombia
  • Gustavo Zuluaga Unidad de Nefrología y Trasplante Renal, Hospital Pablo Tobón Uribe, Universidad de Antioquia, Medellín, Colombia

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How to Cite
1.
Nieto-Ríos JF, Zuluaga M, Serna LM, Aristizábal A, Ocampo-Kohn C, Gálvez KM, et al. Three cases of de novo multiple myeloma after kidney transplantation. biomedica [Internet]. 2016 Dec. 1 [cited 2024 May 16];36(4):498-503. Available from: https://revistabiomedica.org/index.php/biomedica/article/view/3090

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Published
2016-12-01
Section
Case presentation

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