Quality of life in patients with multiple sclerosis and their caregivers in Colombia: One-year follow-up
Abstract
Introduction: Multiple sclerosis is a chronic inflammatory demyelinating disease associated with neurological disability. Clinical features include motor, cerebellar, visual, and sensory function alterations, as well as psychiatric comorbidities, such as depression, anxiety, and irritability. There is little literature available on the quality of life of patients and their caregivers.
Objective: To assess the quality of life of patients with multiple sclerosis and their caregivers in Colombia given that there is no information on the subject in this particular population to establish comprehensive management plans.
Materials and methods: We used the MusiQol and CareQol questionnaires and the Beck Depression Inventory. A prospective analytical observational protocol was designed to include patients aged 18 to 65 years with a diagnosis of relapsing-remitting multiple sclerosis between October, 2014, and October, 2015, at the Hospital Universitario San Ignacio. We evaluated quantitative variables and Spearman correlations. The data analysis was carried out with Student t and Mann-Whitney U tests.
Results: A total of 55 patients with relapsing-remitting multiple sclerosis participated in the study. Chronic fatigue was the most common comorbidity in 27%. The MusiQol questionnaire revealed a good basal quality of life, which remained at similar levels in the follow-ups at six and 12 months. Quality of life was good during the study since there were no statistically significant differences between baseline and follow-up MusiQol scores. Good quality of life was also observed in caregivers.
Conclusions: The quality of life of several Colombian patients diagnosed with multiple sclerosis was very good. This positive result was also observed in caregivers as evidenced by the results of the CareQol questionnaire. We also observed and indicated an inversely proportional correlation between the Expanded Disability Status Scale and the quality of life indexes.
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References
Giesser BS. Diagnosis of multiple sclerosis. Neurol Clin. 2011;29:381-8. https://doi.org/10.1016/j.ncl.2010.12.001
Benedict RH, Bobholz JH. Multiple sclerosis. Semin Neurol. 2007;27:78-85. https://doi.org/10.1055/s-2006-956758
Hilt Pfleger CC, Meulengracht Flachs E, Koch-Henriksen N. Social consequences of multiple sclerosis: Early pension and temporary unemployment-a historical prospective cohort study. Mult Scler. 2010;16:121-6. https://doi.org/10.1177/1352458509352196
Alshubaili AF, Ohaeri JU, Awadalla AW, Mabrouk AA. Family caregiver quality of life in multiple sclerosis among Kuwaitis: A controlled study. BMC Health Serv Res. 2008;8:206. https://doi.org/10.1186/1472-6963-8-206
Tanrverdi D, Okanl A, Sezgin S, Ekinci M. Quality of life in patients with multiple sclerosis in Turkey: Relationship to depression and fatigue. J Neurosci Nurs. 2010;42:267-73.
Opara JA, Jaracz K, Brola W. Quality of life in multiple sclerosis. J Med Life. 2010;3:352-8.
Fernández O, Fernández V, Baumstarck-Barrau K, Muñoz L, González-Álvarez MDM, Arrabal JC, et al. Validation of the Spanish version of the Multiple Sclerosis International Quality of Life (Musiqol) questionnaire. BMC Neurol. 2011;11:127. https://doi.org/10.1186/1471-2377-11-127
Ojeda E, Díaz-Cortés D, Rosales D, Duarte-Rey C, Anaya JM, Rojas-Villarraga A. Prevalence and clinical features of multiple sclerosis in Latin America. Clin Neurol
Neurosurg. 2013;115:381-7. https://doi.org/10.1016/j.clineuro.2012.11.028
Kern S, Schrempf W, Schneider H, Schultheiß T, Reichmann H, Ziemssen T. Neurological disability, psychological distress, and health-related quality of life in MS patients within the first three years after diagnosis. Mult Scler J. 2009;15:752-8. America. Clin Neurol Neurosurg. 2013;115:381-7. https://doi.org/10.1177/1352458509103300
Kobelt G, Berg J, Lindgren P, Fredrikson S, Jönsson B. Costs and quality of life of patients with multiple sclerosis in Europe. J Neurol Neurosurg Psychiatry. 2006;77:918-26. https://doi.org/10.1136/jnnp.2006.090365
Khan F, Pallant J. Chronic pain in multiple sclerosis: Prevalence, characteristics, and impact on quality of life in an Australian community cohort. J Pain. 2016;8:614-23. https://doi.org/10.1016/j.jpain.2007.03.005
Kantarci O, Wingerchuk D. Epidemiology and natural history of multiple sclerosis: New insights. Curr Opin Neurol. 2006;19:248-54.: https://doi.org/10.1097/01.wco.0000227033.47458.82
Janardhan V, Janardhan V, Bakshi R, Bakshi R. Quality of life in patients with multiple sclerosis: The impact of fatigue and depression. J Neurol Sci. 2002;205:51-8. https://doi.org/10.1016/S0022-510X(02)00312-X
Pfleger CC, Flachs EM, Koch-Henriksen N. Social consequences of multiple sclerosis. Part 2. Divorce and separation: A historical prospective cohort study. Mult Scler. 2010;16:878-82. https://doi.org/10.1177/1352458510370978
Dalgas U, Stenager E, Jakobsen J, Petersen T, Hansen HJ, Knudsen C, et al. Fatigue, mood and quality of life improve in MS patients after progressive resistance training. Mult Scler. 2010;16:480-90. https://doi.org/10.1177/1352458509360040
Rivera-Navarro J, Benito-León J, Oreja-Guevara C, Pardo J, Bowakim-Dib W, Orts E, et al. Burden and health-related quality of life of Spanish caregivers of persons with multiple sclerosis. Mult Scler J. 2009;15:1347-55.
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